Dr. Brigham has a background in microbial genetics and microbial physiology. His graduate study focused on sugar utilization in an opportunistic pathogen, Bacteroides fragilis. His postdoctoral study focused on growth of Ralstonia eutropha (now called Cupriavidus necator) and synthesis of a biodegradable plastic, polyhydroxybutyrate (PHB). Dr. Brigham also has led a research group that engineered R. eutropha to produce isobutanol biofuel. His current research focus is on microbial bioprocessing and biomanufacturing.