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Impact of minority stress and resilience on post-traumatic stress disorder symptom severity among a sample of transgender, nonbinary, and gender-expansive individuals
Journal article   Peer reviewed

Impact of minority stress and resilience on post-traumatic stress disorder symptom severity among a sample of transgender, nonbinary, and gender-expansive individuals

Starr Tomlinson, Mark Parshall, Stephen Hernandez, Erick K. Hung, Madeline B. Deutsch, Kristopher Jackson and Sharon Ruyak
Nursing outlook, Vol.73(5), p.102498
09/01/2025
PMID: 40712444

Abstract

Minority stress PTSD Transgender
Transgender, nonbinary, and gender-expansive (TNGE) individuals experience disproportionately high levels of discrimination and violence. These chronic stressors can disrupt stress responses and increase vulnerability to negative mental health outcomes. The purpose of this research was to explore the impact of gender minority stress and resilience on post-traumatic stress disorder (PTSD) symptom severity among TNGE individuals receiving outpatient medical or psychiatric care. Individuals (N = 103) receiving gender-affirming healthcare services at one of two university-affiliated practice settings completed an anonymous survey measuring PTSD symptom severity and gender minority stress and resilience. One-third of participants met provisional criteria for PTSD. No significant differences in PTSD symptoms were found based on assigned sex at birth, current gender identity, marital status, sexual orientation, or race/ethnicity. Distal stressor subscales accounted for approximately 40% of variance in PTSD symptom severity in a hierarchical regression model. Proximal stressors and resilience subscales accounted for an additional 7% and 3% of variance, respectively. TNGE individuals’ experiences of gender minority stress, especially distal stressors, may constitute risk factors for PTSD. Interventions to foster community engagement may offer valuable mental health benefits for TNGE persons. •Gender minority stress contributes to post-traumatic stress disorder (PTSD) symptom severity in transgender, nonbinary, and gender-expansive (TNGE) individuals.•One-third of TNGE individuals in this sample met criteria for PTSD.•Assessing risk for PTSD symptoms may enhance gender-affirming care.

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